ICSI or Intracytoplasmic Sperm Injection is a type of IVF (in vitro preparation) that is most normally utilized in instances of outrageous male fruitlessness, after oocyte conservation (egg freezing), or after rehashed disappointment with the traditional IVF endeavors. Pearl Women’s Hospital is a well-known hospital that provides ICSI treatment in Pune with an experienced and professional team of doctors. The technology is designed to help couples with severe male factor infertility or couples who were unable to fertilize in previous in vitro fertilization (IVF) attempts to achieve fertilization. The system defeats numerous hindrances to preparation and permits couples who have little expectation of an effective pregnancy to get treated with undeveloped organisms.

The procedure requires female partners to use fertility drugs for ovarian stimulation in order to develop several mature eggs. The eggs are then sucked through the vagina utilizing vaginal ultrasound and hatched under exact conditions in the embryology research center. Semen samples are prepared by centrifuging or spinning the sperm through a special medium. This separates live sperm from waste and most of the dead sperm. The embryologist then, at that point gathers a solitary live sperm into a glass needle and infuses it straightforwardly into the egg.

In the case of male factor infertility with abnormal semen analysis, ICSI is considered absolutely necessary. However, approximately 75% of IVF cases are now ICSI. The reasons why patients choose to receive ICSI are not male infertility, including:

• Previous IVF poor fertilization
• Variable sperm count
• Unexplained infertility

If you are told that your sperm test results are abnormal, you should seriously consider ICSI. If the male partner has undergone a vasectomy to reverse, we also recommend ICSI, regardless of sperm quality, because there are sperm antibodies that can affect fertilization.

A few couples pick ICSI on the grounds that they need to do all that could be within reach to expand treatment. In any case, comprehend that for some couples with ordinary sperm boundaries, the most extreme preparation can be accomplished through standard insemination during IVF without utilizing ICSI.

A fertilization rate of 70% to 80% of all injected eggs is currently being achieved, which is equivalent to fertilization with normal sperm, and the pregnancy rate is comparable to that seen during IVF in couples without male factor infertility.

Let it be the fertilization rate achieved through the ICSI program. The fertilization rate in the UCSF IVF laboratory is excellent, currently 80% to 85%. That is, on average, 8 out of 10 eggs will be fertilized normally.

The ICSI procedure is generally considered to be a procedure with relatively low risks. However, ICSI has many risks and disadvantages, just like any aspect of medicine. Once sperm is obtained, the male partner is not susceptible to any risks of surgery. Some of the known risk factors for ICSI include:

• Embryo damage – not all fertilized eggs will eventually become healthy embryos. During the ICSI process, some embryos and eggs may be damaged.
• Multiple pregnancies – Couples who use ICSI in combination with IVF have a 30-35% higher chance of having twins, and a 5%-10% higher chance of triplets. When the mother has multiple births, there is an increased risk of certain complications during pregnancy and delivery, including high blood pressure, gestational diabetes, low amniotic fluid levels, premature delivery, or the need for a C-section.
• Birth defects – 1.5% -3% of the risk of major birth defects in normal pregnancies. ICSI treatment slightly increases the risk of birth defects, although this is rare. In addition, the risk of fertility problems in male offspring is slightly increased. There is a possibility of infertility gene transfer.

ICSI is an option that is definitely worth considering for the treatment of general sexual insufficiency, ejaculation problems, and other problems related to male infertility. People who encounter these problems can definitely benefit from ICSI treatment. It gives male partners the opportunity to use their sperm to give birth to children. Couples can also choose ICSI before choosing donor sperm to obtain live sperm. Even if the man had a vasectomy, ICSI can be performed. In this case, a special sperm extraction technique can be used to extract live sperm directly from the testis and inject it into the egg.

The advantages of utilizing ICSI are clear as a rule, and it is certainly a phenomenal innovation when required. However, in some cases, the success rate is still controversial. What it includes:

• Fewer eggs recovered: When there are few eggs, there is a risk of infertility. In this case, ICSI may be a viable option, but there is no evidence that using ICSI can increase pregnancy or live birth rates.
• Unexplained infertility: In unexplained infertility, the cause of infertility is unknown. However, there is no evidence that the success rate of live births increases when ICSI is used for unexplained infertility.
• High maternal age: Currently, there is no evidence of the effect of high maternal age on the fertilization rate. Therefore, ICSI may not be necessary.
• Routine use of ICSI and IVF: Some reproductive endocrinologists believe that ICSI should be used for each patient to eliminate the possibility of fertilization failure. However, studies have shown that only 1 in 33 patients ultimately benefited from routine ICSI use. Others do not get the benefits associated with ICSI, but they will definitely be at risk.

Pearl Women’s Hospital provides the best ICSI treatment in Pune who has an experienced and highly qualified team of doctors. Pearl Women’s Hospital is a renowned hospital with great infrastructure and best-in-class faculty.